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Exploring Medications for Managing Sleeping Disorders

Muralinath E., Pooja Devi, Nikhil Ch. Nath, Champak B., Kalyan C., Archana Jain, Guruprasad M.

Abstract


        Sleeping disorders influence  a significant  portion  of the  global  population, affecting   overall  well_ being and daily functioning, Benzodiazepines namely bdiazepam and lorazepam behave as central nervous system  depressants.   They increase  the effects  of gamma_ amino butyric acid  (GABA), a neurotransmitter  that  causes  relaxation  as well as sedation.  Non _ benzodiazipine hypnotic  (Z _ drug) namely zolpidem and zaleplon target GABA receptors  and induce a calming effect  along with promotion of sleep.  Z _ drugs are helpful  for treating insomnia.  A very few drugs namely  ramelteon  and tasimelteon mimic theveffects of melatonin, a hormone  that controls the sleep _ wave cycle.  Melatonin  agonists are frequently used for Individuals  with circadian  rhythm  disorders or difficulty  falling asleep.  A very few anti depressants  namely  amitriptyline and trazodone consist of sedative properties.  These drugs alter neurotransmitter  levels  in the  brain and  contribute  neurotransmitter  levelsvin the brain and contribute to a calming effect.  Over_ The _ counter anti histamine namely  diphenhydramine and doxylamine can cause  drowsiness  by inhibiting  histamine  receptors  in the brain.  Finally  it is concluded  that managing sleeping  disorders  frequently  I valves a tailored approach considering  the particular type of sleep disturbance  and Individual characteristics.


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