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A Review On Study of Diabetes Mellitus

Ms. Yogita G. Salunke, Mr. Roshan M. Chaudhary, Mr. Hitendra S. Chaudhary, Dr. S. P. Pawar

Abstract


Diabetes mellitus (DM) also known as simply diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period .This high blood sugar produces the symptoms of frequent urination, increased thirst, and increased hunger. Untreated, diabetes can cause many complications. Acute complications include diabetic ketoacidosis and nonketotic hyperosmolar coma. Serious long-term complications include heart disease, stroke, kidney failure, foot ulcers and damage to the eyes. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. There are three main types of diabetes mellitus:          Type 1 DM results from the body’s failure to produce enough insulin. This form was previously referred to as “insulin-dependent diabetes mellitus”

(IDDM) or “juvenile diabetes”. Apart from a few small adjustments made by theWHO in 1985, not much has changed since then. However, there is a great deal of new

information on the causes of various types of diabetes and more knowledge on how different blood glucose levels can predict the development of diabetic problems. In order to reevaluate diagnostic standards and categorization, a WHO Consultation was held concurrently with a report by an expert committee of the American Diabetes Association.


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References


Onlinelibrary.Wiley. Com

Academic.Oup. Com

American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2006;29: S43–S48.PubMedWorldCat

Homko, C.; Sivan, E.; Chen, X.; Reece, E.A.; Boden, G. Insulin secretion during and after pregnancy in patients with gestational diabetes mellitus. J. Clin. Endocrinol. MeTable 2001, 86, 568–573. [Google Scholar] [CrossRef]

Catalano, P.M. Trying to understand gestational diabetes. Diabet. Med. 2014, 31, 273–

[Google Scholar] [CrossRef] [PubMed] [Green Version]

DeFronzo, R.A. From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus. Diabetes 2009, 58, 773–795. [Google Scholar] [CrossRef] [PubMed] [Green Version]

Zraika, S.; Hull, R.L.; Verchere, C.B.; Clark, A.; Potter, K.J.; Fraser, P.E.; Raleigh, D.P.; Kahn, S.E. Toxic oligomers and islet beta cell death: Guilty by association or convicted by circumstantial evidence? Diabetologia 2010, 53, 1046–1056. [Google Scholar] [CrossRef] [PubMed]

Cai, S.; Tan, S.; Gluckman, P.D.; Godfrey, K.M.; Saw, S.-M.; Teoh, O.H.; Chong, Y.-S.; Meaney, M.J.; Kramer, M.S.; Gooley, J.J.; et al. Sleep Quality and Nocturnal Sleep Duration in Pregnancy and Risk of Gestational Diabetes Mellitus. Sleep 2017, 40. [Google Scholar] [CrossRef] [PubMed]

Facco, F.L.; Grobman, W.A.; Reid, K.J.; Parker, C.B.; Hunter, S.M.; Silver, R.M.; Basner, R.C.; Saade. R; Pien, G.W.; Manchanda, S.; et al. Objectively measured short sleep duration and later sleep midpoint in pregnancy are associated with a higher risk of gestational diabetes. Am. J. Obstet. Gynecol. 2017. [Google Scholar] [CrossRef] [PubMed]

Farr, O.M.; Gavrieli, A.; Mantzoros, C.S. Leptin applications in 2015: What have we learned about leptin and obesity? Curr. Opin. Endocrinol. Diabetes Obes. 2015, 22, 353–

[Google Scholar] [CrossRef] [PubMed]

Williams, M.A.; Qiu, C.; Muy-Rivera, M.; Vadachkoria, S.; Song, T.; Luthy, D.A. Plasma adiponectin concentrations in early pregnancy and subsequent risk of gestational diabetes mellitus. J. Clin. Endocrinol. MeTable 2004, 89, 2306–2311. [Google Scholar] [CrossRef] [PubMed]

Succurro, E.; Marini, M.A.; Frontoni, S.; Hribal, M.L.; Andreozzi, F.; Lauro, R.; Perticone, F.; Sesti, G. Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals. Obesity 2008, 16, 1881–1886. [Google Scholar] [CrossRef] [PubMed]

Glasgow RE, Strycker LA: Preventive Care Practice for Diabetic Management in Two Primary Care Sample Am J Prev Med 2000,19 (1):9-14.10.1016/S0749-3797(00)00157-

Article CAS PubMed Google Scholar

Walker E: Characteristics of the Adult Learner. Diabetes Educ 1999,25 (6supl);16-24 Article CAS PubMed Google Scholar

Bagdade jD, Stewart M Walters E: Impaired granulocytes Adherence. A reversible defect in host defense in patient with Poorly Controlled Diabetic. Diabetes27:677-681,197

Varma S, Maitland A, Weisel R, Li S, Fedak P, Pomroy N, Michel D, Li R, Ko L, Rao V: Hyperglycemia exaggerates ischemia reperfusion – induced cardio myocyte injury. reversal with endothelin antagonism. J Thorac cardiovasc surg123:1120-1124,2002

Morohoshi M, fujisawa K, Uchimura I, Numano F: Glucose- dependent interleukin 6and tumor necrosis factor production by human peripheral blood monocytes in vitro. Diabetes45:954,1996

Mohamed Ali V, Goodrick S, Ravesh A, Katz DR, Miles MJ, Yudkin JS, Klein S, Coppack SW: Subcutanuous adipose tissue release inter leukin-6 but not tumor necrosis factor –alpha, in vivo. J Clin Endocrinol Metab82:4196 -4200,1997

Marfella R, Quagliaro L, Nappo F, Cariello A, Giugliano D: acute hyperglycemia induced an oxidative strees in healthy sub. J Clin invest108:635-636,2001

Prado R, Ginsberg MD, Dietrich WD, Watson BD, Busto R: hyperglycemia increses infact size in collaterally perfused but not end arterial vascular territories. J Cereb Blood Metab 8:186-192,1988

Lazarou C, Panagiotakos D, Matalas AL. The role of diet in prevention and management of type 2 diabetes: implications for public health. Crit Rev Food sic Nutr. 2012;52(5):382–9. Doi: 10.1080/10408398.2010.500258. [PubMed] [Cross Ref] [Google Scholar]

https://diabetes.co.in/what-is-the-prevalence-of-diabetes-in-india-current-data-and- stats/

https://www.mayoclinic.org/diseases-conditions/diabetes/symptoms-causes/syc- 20371444

https://www.mayoclinic.org/diseases-conditions/diabetes/doctors-departments/ddc- 20371453


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