Erabadu (Erythrina Variegate) Leaves against Helminthic Infestation of Children (Purishaja Krimi) - Review

Abstract

Worm infestation present all over the aged group people, but they are mostly problem in children. According to Ayurveda Kirimi is a broad term it includes all the worms which maybe pathogenic or nonpathogenic Pathogenic harmful to human beings helminthiasis specifically can be correlated to Pureshaja type Kirimi. Use of herbal medicine in treatment of worm infestation has been growing because of fewer side effects of molecular medicine. Erythrina variegate is commonly used for traditional medicinal especially Indian type of Erythrina variegate leaves is used for roundworm and thread worm. OBJECTIVE To use the Erythrina variegate leaves for the worm infestation in children as a home remedy and reducing the use of molecular medicine and preventing the complications which can arise from modern medicine and to develop a drug from Erythrina variegate leaves as a pill form. METHODOLOGY: Ayurvedic literature, web-based database searches and published papers data were collected. RESULTS: Phytochemical analysis of Erythrina variegates leaves extract it shows alkaloids, flavonoids, glycosides, saponins, steroids, tannins andterpenoids. Chemical contents, nutrition values and inorganic ions were presented. Higher concentration of Erythrina variegate leaves produced paralytic effects on worms much earlier. Aqueous and methanol extracts of Erythrina variegate leaves exhibited anthelminthic activity Maximum efficacy at 100 and 200mg/ml concentration for worms. More investigation of these Erythrina variegates leaves extract against the helminthic infestation considerate impact on developing clinically achievable strategies to treat children with worm infestation and developing into pill form.