Therapeutic Approaches: Drugs Acting on Uterine Cancer

Abstract

Uterine cancer, also termed as endometrial cancer, is a prevalent cmalignancy, influencing the lining of the uterus. Hormone therapy is a common approach especially fir treating uterine cancer, specifically in cases where the cancer cells are hormone receptor _ positive. Drugs like progestins, namely megesterol acetate or medroxy progesterone acetate, perform by altering hormone levels to inhibit the growth of cancer cells. These therapies are frequently considered for patients who are not candidates for surgery or radiation. Chemotherapy is useful for the treatment of uterine cancer, either as a stand-alone treatment or in combination with surgery or radiation. Drugs such as carboplantin, doxorubicin and paclitaxel are frequently used to target in a rapid manner dividing cancer cells, stopping their growth and spread Ness also. While chemotherapy can be associated with side effects, it's effectiveness in decreasing tumor size and stopping recurrence is well _ established. Targeted therapies focus on particular molecular abnormalities in cancer cells, offering more precise and tailored approach to treatment. For uterine cancer, drugs such as trastuzumab and bevacizumab target specific proteins participated in cancer growth. Treanszumab shows its effectiveness I. Tumors with HER 2 / neu over expression, while bevacizumab stops angiogenesis, disrupting the blood supply to the Timor. Immunotherapy plays an important role in cancer treatment. Drugs such as nivolumab and pembrolizumab perform by increasing the body's immune response against cancer cells. In a very few cases where estrogen plays an important role influencing uterine cancer, aromatase inhibitors namely letrozole may be taken into consideration. These drugs stop the production of estrogen in peripheral tissue, stopping it's stimulating effect specifically on cancer cells. Aromatherapy inhibitors are frequently considered especially in post-menopausal women with hormone receptor_ positive uterine cancer. Finally it is concluded that the treatment landscape for uterine cancer has witnessed an essential advancements in recent years, with a range of drugs offering various therapeutic options.