Drugs Acting on Poly Cystic Ovary Syndrome: A Comprehensive Review

Abstract

Polycystic Ovary SYNDROME ( PCOS ) is a common endocrine disorder influencing individuals, especially women of reproductive age. PCOS is manifested by hormonal imbalances, presence of cysts on the ovaries and irregular menstrual cycles. While lifestyle modifications, namely diet. and exercise are frequently recommend. Pharmaceutical interventions can also play a critical role in managing PCOS symptoms. Met forming is a generally prescribed medication for PCOS, specifically vfor those with insult resistance. It enhances insulin sensitivity. decreasing the elevated insulin levels frequently seen in PCOS. That is why, Metformin can help in the regulation of menstrual cycles and cam help on weight management also. Clomiphene citrate is helpful in inducing ovulation in women with PCOS. It performs by blocking estrogen receptors in the Hypothalamus, resulting enhanced production of follicle _ stimulating hormone ( FSH ) and luteinizing hormone ( LH ). This activation increases the development and release of eggs from the ovaries. In a very few cases, an injectable gonadotropin, namely FSH and LH, may be administered to activate ovulation. This frequently considered if other medications namely Clomiphene are not effective. Careful monitoring is essential to minimize the risk of especially multiple pregnancy. An elevated levels of androgen are common in PCOS. Anti_ androgen namely spironolactone perform by blocking the effects of androgen on rhe skin and hair follicles. This can assist in reducing acne and excessive hair growth ( hirsutism ) associated with PCOS. Birth control pills consisting of a combination of estrogen and protesting can control menstrual cycles and reduce symptoms namely acne and hirsutism. They perform by suppressing ovulation and stabilizing vhormonal fluctuations. Thiazolidinediones enhance insulin sensitivity and can be beneficial for women along with PCOS and insulin resistance. Thiazodinediobes assists tissues regarding response in an effective manner to insulin, contributing to better blood sugar control and regulation of menstrual cycles. Incretin_ based medications ( e g., exenatide) , originally developed for type 2 diabetes, may exhibit positive effects on PCOS. These drugs increase insulin secretion and may enhance ovarian activity, though mire research is required to establish their role definitively. Finally it is concluded that before starting any medication , individuals should consult with their health care provider to estimate the most appropriate treatment plan for their unique requirements.