Exploring Drugs Acting on Persistent Corpus Luteum

Abstract

The corpus luteum is a critical component in the female reproductive tract, formed from particularly from the ruptured follicle after ovulation. It's utmost important activity is to produce progesterone, a hormone vital for regulating the uterine lining during the menstrual cycle. Whatever it may be, in a very few cases, the corpus luteum may persist for longer duration than usual, resulting in hormonal imbalances and potential reproductive issues. Hormonal imbalances may interfere with Nirmal menstruation and prevent conception. Prolonged elevation of progesterone can influence the endometrial lining, potentially resulting in inertility or recurrence pregnancy loss. GnRH agonists namely leuprolide, prevent the release of gonadotropin s, resulting in a temporary reduction especially in ovarian activity. This assists in stopping the function of the persistent corpus luteum. Drugs such as mifepristone can stop the function of progesterone bt binding to its receptors. Non steroidal anti_ inflammatory drugs such as I unproven, can decrease prostaglandin synthesis, potentially influencing corpus luteum function. Side effects of NSAID drugs include hot flashes, mood swings and changes in bone density, emphasizing the importance of careful monitoring. Finally it is concluded that drugs targeting the persistent corpus luteum play a critical role in restoring hormonal balance and addressing reproductive challenges.