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Drugs Acting on Thyroid Hormones

Muralinath E., Pooja Devi, Prasanta Chbukdhara, Sanjib Borah, Kalyan C., Archana Archana Jain, Guruprasad M.

Abstract


Thyroid hormones play a critical role in controlling many physiological processes in the human body along with energy balance and Metabolism. Hyperthyroidism is manifested by an overactive thyroid gland. Antithyroid medications namely methimazole and propyl thiouracil. Beta blockers such as propranolol manage the symptoms of thyroid storm. Radioactive iodine is useful in treating hyperthyroidism. Iodine acts as an important element for thyroid hormone synthesis. Iodine deficiency can result in thyroid disorder. Iodine supplementation namely potassium iodide (KI) may be prescribed b in regions where Iodine is absent. Whatever it may be, excessive Iodine intake also disturbs thyroid function. Thyroid hormone receptor agonist namely eprotirome mimic the effects of thyroid hormones. Thyroid hormone receptor antagonist such as resmetirom stops the action of thyroid hormones and is investigated for conditions such as hypercholesterolemia. It is finally concluded that drugs acting on thyroid hormones are vital for controlling the balance of these crucial regulators of physiological processes.


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