Identification of Early as well as Advanced Symptoms of B1 Deficiency Along With Neurological, Cardiac And Gastro Intestinal Manifestations

Abstract

Thiamine, also termed as thiamin and vitamin B1, is one of the 8 B-complex vitamins and is categorized as a water-soluble B vitamin. Thiamine happens  naturally in specific diets, is included in food products, and is available in dietary supplements. Brown rice, whole grains, pork, poultry, soybeans, nuts, peas, dried beans, and fortified or enriched grain products namely bread, cereals, and infant formulas are rich sources of thiamine. Multivitamins supplement an additional 1.5 mg of thiamine to a diet already excess in this essential vitamin.

Wernicke-Korsakoff syndrome can occur in people with persistent or untreated vitamin B1 deficiency if they experience advanced-stage symptoms. Thiamine is approved by the United States Food and Drug Administration (FDA) paricularly for the treatment of Wernicke encephalopathy, infantile beriberi, and cardiovascular disease leading to thiamine deficiency. Vitamin B1 deficiency may present with early or advanced symptoms. Early symptoms mainly arise from neurological, cardiac, and gastrointestinal systems. Due to thiamine's restricted  storage duration before rapid excretion, regulating essential  blood serum levels needs a consistent and regular dietary intake. The indications, mode of action, methods of administration, major side effects, contraindications, and monitoring protocols—specifically for vitamin B1—are all explained in this activity. Along with increasing patient outcomes, this exercise prepares clinicians to work as part of an interprofessional team with dieticians, pharmacists, and primary care physicians to assist patient therapy in treatment or supplementation settings when thiamine is necessary.