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Medications for Managing Emphysema: A Comprehensive Guide

Muralinath E., Pooja Devi, Nikhil Ch. Nath, Champak B., Kalyan C., Archana Jain, Guruprasad M.

Abstract


Emphysema  is a chronic  respiratory  condition  manifested  by the gradual destruction  of lung tissue, resulting  in difficulty regarding  breathing.  Broncodilators perform by relaxing g the smooth muscles of the airways, causing  it easier for individuals  with emphysema  to breathe. There arectwo  main types of broncho dilator namely Vantin cholinergic and beta _ agonists.  Beta_ agonist  namely  albuterol and salmeterol activate beta receptors  in the airways, resulting In bronchial dilatation  and enhanced airflow. Anticholinergic namely  tiotropium stop the action. Of acetyl. Choline, a neurotransmitter  that constric the airways.  Anticholinergic enhances brochure dilatation  and easy breathing difficulties  also.  Inhaled  corticosteroids  namely  budesonide and flymuticasone are  frequently  prescribed  along with  bronchi dilator. Phospho desperate _ 4  ( PDE _ 4 )  inhibitors ( Roflumilast )  is used regarding  the treatment  of severe  emphysema.  Roflumilast assists in decreasing  inflammation  and relax the airways by inhibiting  the action. Of PDE _ 4, an enzyme  participated in the inflammatory  process.  In advanced stages of emphysema,  if oxygen levels in the blood are low, supplemental oxygen plays an important  role.  Administered through  nasal prognosis or masks, oxygen therapy assists in increasing   oxygenation, alleviate  symptoms and increasing overall quality. Finally  it is concluded  that medications  play an important role in managing  symptoms  and slowing down disease progression that is emphysema.


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