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Understanding Drugs Acting on Parathyroid Hormones: A Comprehensive Overview

Muralinath E., Pooja Devi, Prasanta Chbukdhara, Sanjib Borah, Kalyan C., Archana Jain, Guruprasad M.

Abstract


      The parathyroid glands are crucial in controlling the body's calcium balance. Parathormone affects the intestines, kidneys, and bones.  Hyper parathyroidism enhance calcium levels in the blood. Calcimetrics namely cinaclcet mimic the action of the parathyroid  glands, thereby decreasing  PTH secretion.  Biphosphonates like alendronate is useful in treating hyperparathyroidism by decreasing  bone resorption. Hypo parathyroidism happens due to an insufficient  production  of PTH.  Hypothyroidism  needs supplementation with  calcium  and vitamin D. Calcium carbonate  and calcium  citrate are helpful in treating  hypo parathyroidi msm.  Vitamin D analogues such as alpha calcium and cacitriol play a role in increasing  calcium  absorption  from the intestines.  Synthetic parathyroid hormone ( teriparatide) is used regarding  treatment  of hypo parathyroidism. Finally it is concluded that drugs acting on parathyroid hormones play a role particularly  in managing disorders regarding  calcium homeostasis.


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References


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