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Drugs and their Role in Amniocentesis: A Comprehensive Overview

Guruprasad M., Muralinath E., Singh H. S., Vijay Digamber D., Shraddha D., Lalit Kumar S., Kalyan C., Archana Jain

Abstract


Amniocentesis is a medical procedure performed especially during pregnancy to collect valuable I formation regarding the development of fetus. This prenatal Diagnostic test is linked to the extraction of amniotic fluid surrounding the fetus especially for different analyses namely chromosomal abnormalities, genetic disorders and other developmental issues. Before starting amniocentesis, healthcare professionals frequently use local anesthetics to numb the abdominal area where the needle will be inserted. Generally used anesthetics include lidocaine and bupivacaine. In a very few cases, antibiotics may be helpful prior to aminocentesis to decrease the risk of infection. For Rh_ negative mother's, Rho ( D ) immune globulin ( RhoGAM) may play a role in preventing Rh I compatability issues. Rh incompatibility can result in serolious complications especially for future pregnancies, making Rho GAM a vital preventive measure Betamethadone or dexa methadone is to be given to the mother in advance to enhanced fetal lung development. Very few women may have some discomfort or cramping following amniocentesis. Healthcare professionals may suggest over-the-counter pain relievers, such as acetaminophen, to treat any post-procedural pain. Finally it is concluded that while amniocentesis is essentially a diagnosis procedure, the use of certain drugs increases it's safety as well as effectiveness.


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