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Drugs Acting on Fetal Growth Abnormalities: A Comprehensive Overview

Muralinath E., Singh H. S., Vijay Digamber D, Shraddha D., Lalit Kumar S, Kalyan C., Archana Jain, Guruprasad M.

Abstract


Fetal growth abnormalities  pose a challenge  on a significant  manner to maternal and child health, influencing  well_ being of both mother and baby.  Many factors  such as environmental, genetic and maternal conditions, can correlate with deviations particularly  in fetal growth.  Folic acid is a critical B_ vitamin that plays an important  role in fetal development  particularly  in the early stages of pregnancy.  Deficiencies of folic acid  can result in neural tube defects as well as growth abnormalities.   Growth  hormone therapy activates skeletal and organ growth particularly  regarding the development  of fetus. Low_ dose aspirin helps in stopping  pre_ eclampsia and fetal growth. Pre eclampsia , a condition  manifested by high blood pressure, can result in restricted blood flow to the fetus, influencing  it's growth. Corticosteroids  namely  betamethasone, are  used if preterm birth is imminent. These  drugs assist in enhancing  fetal lung maturation  and decrease the risk of respiratory  distress syndrome ( RDS ) , frequently  associated  with preterm births.  Antibiotics  may be preferred  to treat infections,  stopping  their potential  impact on the developing  fetus Gestational  diabetes plays an important  role regarding fetal over growth  ( macrosimia ). An administration  of magnesium  sulfate is required especially  in cases of preterm labor  to provide protection  to the fetal brain especially  from potential  damage. It is essentially is seen in Cerebral palsy. Finally  it is concluded  that drugs play a critical role especially  in managing These abnormalities.


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References


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