Open Access Open Access  Restricted Access Subscription Access

An Essential Parameters of Glycogenolysis Include Fundamentals, Molecular Level, Function, Mechanism and Clinical Significance

Muralinath E., Guruprasad M., Madhavi Latha C., Sheethal U., Vyshnavi J., Varsha V., Prathysha M.V.S., Karthik Jayanyj Y.

Abstract


Glycogen, also termed as animal starch, is a branched polysaccharide that behaves as an energy reserve in the liver and muscle. It is readily available as an immediate source of energy. The formation of glycogen from glucose is otherwise known as glycogenesis, and the breakdown of glycogen to form glucose is also termed as glycogen metabolism or glycogenolysis. Glycogenolysis is the breakdown of glycogen caused by increased cyclic adenosine monophosphate (cAMP).


Full Text:

PDF

References


Tadaishi, M., Toriba, Y., Shimizu, M., & Kobayashi-Hattori, K. (2018). Adenosine stimulates hepatic glycogenolysis via adrenal glands–liver crosstalk in mice. PLOS ONE, 13(12), e0209647. https://doi.org/10.1371/journal.pone.0209647

Ellingwood, S. S., & Cheng, A. (2018). Biochemical and clinical aspects of glycogen storage diseases. Journal of Endocrinology, 238(3), R131–R141. https://doi.org/10.1530/JOE-18-0120

Panja, S., Patra, S., Mukherjee, A., Basu, M., Sengupta, S., & Dutta, P. K. (2013). A closed-loop control scheme for steering steady states of glycolysis and glycogenolysis pathway. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 10(4), 858–868. https://doi.org/10.1109/TCBB.2013.77

Huijing, F. (1975). Glycogen metabolism and glycogen-storage diseases. Physiological Reviews, 55(4), 609–658. https://doi.org/10.1152/physrev.1975.55.4.609

Kishnani, P. S., Austin, S. L., Arn, P., Bali, D. S., Boney, A., Case, L. E., Chung, W. K., Desai, D. M., El-Gharbawy, A., Haller, R., Smit, G. P. A., Smith, A. D., Hobson-Webb, L. D., Wechsler, S. B., Weinstein, D. A., & Watson, M. S. (2010). Glycogen storage disease type III diagnosis and management guidelines. Genetics in Medicine, 12(7), 446–463. https://doi.org/10.1097/GIM.0b013e3181e655b6

Coggan, J. S., Keller, D., Calì, C., Lehväslaiho, H., Markram, H., Schürmann, F., & Magistretti, P. J. (2018). Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate. PLOS Computational Biology, 14(8), e1006392. https://doi.org/10.1371/journal.pcbi.1006392

Biazi, G. R., Frasson, I. G., Miksza, D. R., de Morais, H., de Fatima Silva, F., Bertolini, G. L., & de Souza, H. M. (2018). Decreased hepatic response to glucagon, adrenergic agonists, and cAMP in glycogenolysis, gluconeogenesis, and glycolysis in tumor-bearing rats. Journal of Cellular Biochemistry, 119(9), 7300–7309. https://doi.org/10.1002/jcb.26969

Nadeau, O. W., Fontes, J. D., & Carlson, G. M. (2018). The regulation of glycogenolysis in the brain. Journal of Biological Chemistry, 293(19), 7099–7107. https://doi.org/10.1074/jbc.R117.000180

Villar-Palasi, C., & Larner, J. (1970). Glycogen metabolism and glycolytic enzymes. Annual Review of Biochemistry, 39, 639–672. https://doi.org/10.1146/annurev.bi.39.070170.003231

Raza, M., Arif, F., Giyanwani, P. R., Azizullah, S., & Kumari, S. (2017). Dietary therapy for Von Gierke’s disease: A case report. Cureus, 9(8), e1548. https://doi.org/10.7759/cureus.1548

McCall, A. L., Salemi, J., Bhanap, P., Strickland, L. M., & Elmallah, M. K. (2018). The impact of Pompe disease on smooth muscle: A review. Journal of Smooth Muscle Research, 54, 100–118. https://doi.org/10.1540/jsmr.54.100

Kohler, L., Puertollano, R., & Raben, N. (2018). Pompe disease: From basic science to therapy. Neurotherapeutics, 15(4), 928–942. https://doi.org/10.1007/s13311-018-0655-y

Sentner, C. P., Hoogeveen, I. J., Weinstein, D. A., Santer, R., Murphy, E., McKiernan, P. J., Steuerwald, U., Beauchamp, N. J., Taybert, J., Laforêt, P., Petit, F. M., Hubert, A., Labrune, P., Smit, G. P. A., & Derks, T. G. J. (2016). Glycogen storage disease type III: Diagnosis, genotype, management, clinical course and outcome. Journal of Inherited Metabolic Disease, 39(5), 697–704. https://doi.org/10.1007/s10545-016-9936-2

Nielsen, T. L., Pinós, T., Brull, A., Vissing, J., & Krag, T. O. (2018). Exercising with blocked muscle glycogenolysis: Adaptation in the McArdle mouse. Molecular Genetics and Metabolism, 123(1), 21–27. https://doi.org/10.1016/j.ymgme.2017.10.007


Refbacks

  • There are currently no refbacks.