A review on plant derived mucilage and their application as a excipient

Abstract

Natural mucilages are being integrated into novel drug delivery systems (NDDS) to serve multiple functions, including controlling the rate of drug release. Extensive research is focused on developing safe and effective mucilage-based particulate drug delivery systems, covering aspects such as isolation, purification, standardization, and characterization of natural gums and mucilages. There is a growing trend towards using plant-based and natural products to replace synthetic additives, driven by global interest in natural drugs and excipients. Natural mucilages offer advantages over synthetic ones due to their chemical inertness, non-toxicity, cost-effectiveness, and widespread availability. Flaxseed, also known as linseed, is celebrated for its nutritional richness, primarily containing omega-3 fatty acids, dietary fiber, and lignans. Holy Basil seeds, commonly known as Tulsi seeds, hold cultural and medicinal significance. They are rich in antioxidants and possess antimicrobial properties. Psyllium seeds, recognized as Isabgol or Psyllium husk, are abundant in soluble fiber, aiding digestive health and serving as a natural laxative. Their potential in managing cholesterol levels and regulating blood sugar makes them beneficial for heart health and diabetes management. These seeds offer diverse nutritional and medicinal benefits, ranging from heart health and digestive support to antioxidant protection and traditional therapeutic use. Their incorporation into diets promotes overall well-being and offers a natural approach to addressing various health concerns