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Cortisol Lowering Effect of Cyperus Esculentus in Normal Weight Male Human Subjects
Abstract
Tigernut contains active ingredients such as sterols, alkaloids, tannins, saponins, resins and vitamins E and C. The study investigated how the Tigernut could influence the human blood cortisol level in the normal weight male human subjects under resting condition. A total of forty (40) subjects were involved in the study. They were likewise non-habitual Tigernut chewers and aged 18-28 years were used for the study. Having taken the anthropometric data of the control subjects, they relaxed for the duration of 1hour 30 minutes. Cortisol hormone level was determined according to the method of Tiez and Andresen, using ELISA TECO kit for cortisol. In respect to the test subjects and on a different day entirely, 5g of the Tigernut was administered to each of them to be chewed as a bolus. It should be noteworthy that the same subjects used as control subjects were also used as the test subjects. After ingestion of the Tigernut, 50ml of water was given to each volunteer to flush the masticated Tigernut down the gut. The subjects were likewise allowed to rest for 1hour 30 minutes after which another blood cortisol level was taken. Statistical analyses were carried out using Graph Pad Prism Statistical Software Version 8.1. The results showed that the Tigernut significantly decreased (P < 0.05) the blood cortisol level after its consumption (from 13.36 ± 0.408 to 5.663 ± 0.139 µg/dl). Summarily, the Tigernut was observed to have a blood Cortisol lowering effect in the normal weight male human subjects.
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