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Review on the wound healing effects of the chitosan polymer found in the peel of Luffa cylindrica fruit

Devshree Yashwantbhai Patel, Dr. Javesh K. Patil, Harsha V. Chaudhari, Aniket. R. Girase

Abstract


Chitosan, a natural, biocompatible, and biodegradable biopolymer, is widely thought to have moisturising, antibacterial, and a variety of biological functions for clinical use. Chitosan and its derivatives have received a lot of attention because of its therapeutic characteristics for wound healing.Chitosan accelerates wound healing by activating inflammatory cells, macrophages, and fibroblasts, in order improve the inflammatory phase. Chitosan can be used to prevent or treat wound and burn infections due to its intrinsic antibacterial qualities as well as its capacity to transfer extrinsic antimicrobial medications to wounds and burns. It can also be utilised as a slow-release drug-delivery vehicle for growth factors, which can help with wound healing. Wound healing is the process by which a live entity replaces destroyed or damaged tissue with newly generated tissue. The sponge gourd (Luffa cylindrica) is a popular cultivated vegetable and medicinal plant in the Cucurbitaceae family. Anti-inflammatory, analgesic, anticancer, hepatoprotective, antibacterial, and wound healing activities are found in the leaves, seeds, and fruits of L cylindrica. It was found that the peel of L. Cylindrica contained the highest amount of chitosan. Therefore , In this paper we are focusing on the wound healing activity of peels of L .cylindrica which has highest concentration of chitosan.


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