Open Access Open Access  Restricted Access Subscription Access

Understanding Drugs Targeting Tibial Nerve Paralysis: A Comprehensive Overview

Muralinath E., Jayinder Paul Singh. G, Pradip Kumar Das, Panjan Ghosh P., Kinsuk Das S, Kalyan C., Archana Jain, Guruprasad M.

Abstract


Tibial nerve paralysis, a condition thar influences the tibial nerve, can result in a significant impairment. Motor and sensory functions of the lower limb. Nonsteroidal anti_ inflammatimiry drugs (NSAIDs) play n important role especially on managing tibial nerve paralysis by decreasing inflammation and alleviating associated pain. These drugs namely ibuprofen and naproxen, may be a part of comprehensive treatment plan to address the inflammatory response that can a company nerve i juries. Corticosteroids, namely prednisone, are potent anti_ inflammatory agents that can assist in decreasing swelling and inflammation around the affected ti isl nerve. Medications namely gabapentin and pregabalin, generally used for neuropathic Pain, can show beneficial effect in managing Pai. Related to tibial nerve paralysis Drugs namely baclofen or tizanidine are helpful in relieving stiffness and muscle spasms resulting from tibial nerve paralysis. These drugs perform by acti g on the central nervous system to decrease abnormal muscle contractions Nerve growth factors show beneficial effect regarding the regeneration of the tibial nerve. Medications may be helpful in conjunction with physical therapy to intensity the rehabilitation process In severe cases of tibial nerve paralysis, surgical optio s may be taken into consideration. Finally it us concluded that addressing tibial nerve paralysis involves a multifaceted approach and Medications plat an important role in managing symptoms, decreasing inflammation and facilitating nerve recovery.

 


Full Text:

PDF

References


Torres, A. L. G., & Ferreira, M. C. (2012). Study of the anatomy of the tibial nerve and its branches in the distal medial leg. Acta ortopedica brasileira, 20, 157-164.

Singh, G., & Kumar, V. P. (2012). Neuroanatomical basis for the tarsal tunnel syndrome. Foot & ankle international, 33(6), 513-518.

Nitz, A. J., Dobner, J. J., & Kersey, D. (1985). Nerve injury and grades II and III ankle sprains. The American journal of sports medicine, 13(3), 177-182.

Kuran, B., Aydog, S. E. D. A. T., Ercalik, C., Arda, P., Yilmaz, F., Dogu, B., ... & Durlanik, G. (2017). Medial calcaneal neuropathy: A rare cause of prolonged heel pain. Agri-the journal of the turkish society of algology, 29(1).

Bruce, B. G., Bariteau, J. T., Evangelista, P. E., Arcuri, D., Sandusky, M., & DiGiovanni, C. W. (2014). The effect of medial and lateral calcaneal osteotomies on the tarsal tunnel. Foot & ankle international, 35(4), 383-388.

González-Martín, D., Herrera-Pérez, M., Ojeda-Jiménez, J., Rendón-Díaz, D., Valderrabano, V., & Pais-Brito, J. L. (2021). Neurological injuries after calcaneal osteotomies are underdiagnosed. Journal of Clinical Medicine, 10(14), 3139.

Yammine, K., Daher, J. C., Tannoury, E. H., & Assi, C. (2022). Tarsal tunnel syndrome secondary to accessory or variant muscles: a clinical and anatomical systematic review. Surgical and Radiologic Anatomy, 44(5), 645-657.

Rinkel, W. D., Cabezas, M. C., van Neck, J. W., Birnie, E., Hovius, S. E., & Coert, J. H. (2018). Validity of the Tinel sign and prevalence of tibial nerve entrapment at the tarsal tunnel in both diabetic and nondiabetic subjects: a cross-sectional study. Plastic and reconstructive surgery, 142(5), 1258-1266.

Baylan, S. P., Paik, S. W., Barnert, A. L., Ko, K. H., Yu, J., & Persellin, R. H. (1981). Prevalence of the tarsal tunnel syndrome in rheumatoid arthritis. Rheumatology, 20(3), 148-150.

Dellon, A., Muse, V., & Scott, N. (2012). A positive Tinel sign as predictor of pain relief or sensory recovery after decompression of chronic tibial nerve compression in patients with diabetic neuropathy. Journal of reconstructive microsurgery, 28(04), 235-240.

Singer, A. D., Huynh, T., Wong, P., Sharma, G. B., Gonzalez, F., Umpierrez, M., ... & Moore, T. J. (2019). CT can stratify patients as low risk for tibial neuropathy following a talus fracture. Emergency Radiology, 26, 541-548.

Fantino, O. (2014). Role of ultrasound in posteromedial tarsal tunnel syndrome: 81 cases. Journal of ultrasound, 17, 99-112.

SM, J. S., Didehdar, D., & AR, M. E. (2007). Tibial and peroneal nerve conduction studies in ankle sprain. Electromyography and clinical neurophysiology, 47(6), 301-304.

Patel, A. T., Gaines, K., Malamut, R., Park, T. A., Toro, D. R. D., & Holland, N. (2005). Usefulness of electrodiagnostic techniques in the evaluation of suspected tarsal tunnel syndrome: an evidence‐based review. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine, 32(2), 236-240.

Kavlak, Y., & Uygur, F. (2011). Effects of nerve mobilization exercise as an adjunct to the conservative treatment for patients with tarsal tunnel syndrome. Journal of manipulative and physiological therapeutics, 34(7), 441-448.

Rosson, G. D., Larson, A. R., Williams, E. H., & Dellon, A. L. (2009). Tibial nerve decompression in patients with tarsal tunnel syndrome: pressures in the tarsal, medial plantar, and lateral plantar tunnels. Plastic and reconstructive surgery, 124(4), 1202-1210.

Hossain, M., & Makwana, N. (2011). “Not Plantar Fasciitis”: the differential diagnosis and management of heel pain syndrome. Orthopaedics and trauma, 25(3), 198-206.

Ferkel, E., Davis, W. H., & Ellington, J. K. (2015). Entrapment neuropathies of the foot and ankle. Clinics in Sports Medicine, 34(4), 791-801.

Tu, P. (2018). Heel pain: diagnosis and management. American family physician, 97(2), 86-93.

Kim, D. H., Cho, Y. J., Ryu, S., Tiel, R. L., & Kline, D. G. (2003). Surgical management and results of 135 tibial nerve lesions at the Louisiana State University Health Sciences Center. Neurosurgery, 53(5), 1114-1125.


Refbacks

  • There are currently no refbacks.