Open Access
Subscription Access
An Essential Parameters of Fever in Neonates Include Objectives, Pathophysiology, Toxicokinetics, Diagnosis, Differential Diagnosis and Treatment
Abstract
The World Health Organization categorizes neonatal sepsis as early or late dependent upon the age of onset. Early neonatal sepsis impacts infants less than 72 hours of age ( some experts will extend it to 7 days), whereas late-onset infections are observed in infants between 72 hours and 28 days of age. Reducing the substantial morbidity and mortality in this age group associated with neonatal sepsis depends in large part on early detection and treatment. The presentation, assessment, and treatment of neonatal sepsis are explained in this exercise.
References
Shah, B. A., & Padbury, J. F. (2014). Neonatal sepsis: An old problem with new insights. Virulence, 5(1), 170-178. [PMC free article] [PubMed].
Qazi, S. A., & Stoll, B. J. (2009). Neonatal sepsis: A major global public health challenge. Pediatric Infectious Disease Journal, 28(1 Suppl), S1-S2. [PubMed].
Simonsen, K. A., Anderson-Berry, A. L., Delair, S. F., & Davies, H. D. (2014). Early-onset neonatal sepsis. Clinical Microbiology Reviews, 27(1), 21-47. [PMC free article] [PubMed].
Laptook, A. R., Bell, E. F., Shankaran, S., Boghossian, N. S., Wyckoff, M. H., Kandefer, S., Walsh, M., Saha, S., & Higgins, R., Generic and Moderate Preterm Subcommittees of the NICHD Neonatal Research Network. (2018). Admission temperature and associated mortality and morbidity among moderately and extremely preterm infants. Journal of Pediatrics, 192, 53-59.e2. [PMC free article] [PubMed].
Aronson, P. L., McCulloh, R. J., Tieder, J. S., Nigrovic, L. E., Leazer, R. C., Alpern, E. R., Feldman, E. A., Balamuth, F., Browning, W. L., & Neuman, M. I., Febrile Young Infant Research Collaborative. (2019). Application of the Rochester Criteria to identify febrile infants with bacteremia and meningitis. Pediatric Emergency Care, 35(1), 22-27. [PMC free article] [PubMed].
Gomez, B., Mintegi, S., Bressan, S., Da Dalt, L., Gervaix, A., Lacroix, L., European Group for Validation of the Step-by-Step Approach. (2016). Validation of the “Step-by-Step” approach in the management of young febrile infants. Pediatrics, 138(2). [PubMed].
Wallace, S. S., Brown, D. N., & Cruz, A. T. (2017). Prevalence of concomitant acute bacterial meningitis in neonates with febrile urinary tract infection: A retrospective cross-sectional study. Journal of Pediatrics, 184, 199-203. [PubMed].
Greenhow, T. L., Hung, Y. Y., & Pantell, R. H. (2016). Management and outcomes of previously healthy, full-term, febrile infants ages 7 to 90 days. Pediatrics, 138(6). [PubMed].
Puopolo, K. M., & Eichenwald, E. C. (2010). No change in the incidence of ampicillin-resistant, neonatal, early-onset sepsis over 18 years. Pediatrics, 125(5), e1031-e1038. [PubMed].
Muller-Pebody, B., Johnson, A. P., Heath, P. T., Gilbert, R. E., Henderson, K. L., Sharland, M., iCAP Group (Improving Antibiotic Prescribing in Primary Care). (2011). Empirical treatment of neonatal sepsis: Are the current guidelines adequate? Archives of Disease in Childhood: Fetal and Neonatal Edition, 96(1), F4-F8. [PubMed].
Hyde, T. B., Hilger, T. M., Reingold, A., Farley, M. M., O'Brien, K. L., & Schuchat, A., Active Bacterial Core Surveillance (ABCs) of the Emerging Infections Program Network. (2002). Trends in incidence and antimicrobial resistance of early-onset sepsis: Population-based surveillance in San Francisco and Atlanta. Pediatrics, 110(4), 690-695. [PubMed].
Madhi, F., Jung, C., Timsit, S., Levy, C., Biscardi, S., Lorrot, M., Grimprel, E., Hees, L., Craiu, I., Galerne, A., Dubos, F., Cixous, E., Hentgen, V., Béchet, S., Urinary-tract infection due to extended-spectrum beta-lactamase–producing enterobacteriaceae in children group. Bonacorsi, S., & Cohen, R. (2018). Febrile urinary-tract infection due to extended-spectrum beta-lactamase-producing enterobacteriaceae in children: A French prospective multicenter study. PLOS ONE, 13(1), e0190910. [PMC free article] [PubMed].
Aronson, P. L., Wang, M. E., Shapiro, E. D., Shah, S. S., DePorre, A. G., McCulloh, R. J., Pruitt, C. M., Desai, S., Nigrovic, L. E., Marble, R. D., Leazer, R. C., Rooholamini, S. N., Sartori, L. F., Balamuth, F., Woll, C., & Neuman, M. I., Febrile Young Infant Research Collaborative. (2018). Risk stratification of febrile infants ≤60 days old without routine lumbar puncture. Pediatrics, 142(6). [PMC free article] [PubMed].
Refbacks
- There are currently no refbacks.