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An Extensive Review of Medicines With Anti-Diabetic Effects
Abstract
Hyperglycemia is the primary symptom of diabetes mellitus, a chronic, progressive, and poorly understood metabolic disease. The pathophysiology of type 2 diabetes (T2DM) is thought to be primarily caused by impaired insulin secretion, resistance to the tissue actions of insulin, or a combination of the two. T2DM is a spectrum disease that begins with tissue insulin resistance and gradually progresses to a state where the beta cells in the pancreas completely stop secreting. The significant increase in the prevalence of non-communicable diseases that affect both industrialized and developing countries is largely due to type 2 diabetes. In this brief overview, we want to summarize the current pharmacologic management guidelines, along with the range of drugs currently utilized for this purpose, in order to control the increased blood glucose levels.
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