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An Important Parameters of Physiology of Fetal Circulation Include Development, Mechanism, Pathophysiology, Clinical Significance and Treatment

Srinivas G., Ramanjaneyulu D. V., Muralinath E., Guruprasad M., Sravani Pragna K., Manjari P., Sony Sharlet E., T. Nikhil, V. Yaswanth Sai, D. Kusuma Latha, R. Faith Rani, P. Megha Varna

Abstract


In instance, the fetal circulation system differs significantly from the adult circulation system. This intricate system permits the fetus to gain oxygenated blood and nutrients from the placenta. It consists of the blood vessels especially in the placenta and the umbilical cord, which consists of two umbilical arteries and one umbilical vein. Fetal circulation bypasses the lungs with the help of a shunt termed as the ductus arteriosus; the liver is also bypassed with the help of the ductus venosus, and blood can travel especially from the right atrium to the left atrium with the help of the foramen ovale. Normal fetal heart rate is between 110 and 160 beats per minute. When compared to adults, fetuses exhibit reduced ventricular filling and reduced contractility. Fetal circulation undergoes a rapid transition particularly after birth to accommodate extra-uterine life. Human understanding of fetal circulation formed from fetal sheep, but ultrasound and magnetic resonance imaging (MRI) during the fetal period now yield detailed information. There are distinct differences in fetal circulation that, if not appropriately formed, can result in childhood or adult diseases.


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References


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