Application of Micromachining Techniques in Biomedical Device Fabrication

Abstract

Micromachining has emerged as a critical technology in the miniaturization of devices across diverse industries, particularly in biomedical applications where precision and biocompatibility are essential. This paper presents a case study on the development of a microfluidic chip using micromachining techniques such as micro-electrical discharge machining (µEDM) and laser micromachining. The study focuses on the fabrication of microchannels on a PMMA (Polymethyl Methacrylate) substrate for lab-on-chip diagnostic applications. Key process parameters including pulse energy, feed rate, and laser scanning speed were optimized to achieve desired surface quality, dimensional accuracy, and minimal thermal damage. Experimental results revealed that a hybrid approach combining µEDM for cavity formation and laser micromachining for fine surface structuring provided superior performance over standalone processes. The fabricated chip was tested for fluid flow characteristics, confirming its suitability for bioassay testing. This case study highlights the effectiveness of micromachining in achieving micro-scale features with high precision, supporting the growing demand for portable, cost-effective, and high-performance biomedical diagnostic devices.

Cite as:

Pranesh Bamankar, & A. Awasare. (2025). Application of Micromachining Techniques in Biomedical Device Fabrication. Recent Trends in Automation and Automobile Engineering, 8(2), 27–33. 

https://doi.org/10.5281/zenodo.16030657