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A Survey on Identifications of Hotspots using DSP Methods

G.S.L. B.V. Prasanthi, Ayesha Naaz, Afshan Kaleem

Abstract


Most of the cellular processes are achieved by proteins. They function by interacting with the other proteins which is known as protein-protein interaction (PPI). In PPI, the identification of hot-spots (Protein-target binding sites) is challenging and crucial as it implies characterizing the functionality of PPI. Of the computational techniques with which the hot spots can be identified, Digital Signal Processing (DSP) methods were found to be efficient and powerful tools. In this paper, different DSP methods for the identification of hotspots are reviewed.


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