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Exploring Pharmacological Interventions for Paraplegia: A Hopeful Path Forward

Srinivas G., Ramanjaneyulu D. V., Muralinath E., Guruprasad M., Sravani Pragna K., Manjari P., Sony Sharlet E., T. Nikhil, V. Yaswanth Sai, D. Kusuma latha, R. Fath Rani, P. Megha Varna

Abstract


Paraplegia, a condition manifested by the loss of motor and sensory function in the lower extremities, frequently results from Spinal cord injuries. Healthcare professionals can successfully raise WBC levels and enhance patient outcomes by determining and treating the underlying reasons. AP has exhibited good results in Spinal cord injury related conditions, including vparaplegia. Neurotoxin factors namely brain derived neurotoxin factor ( BDNF ) and nerve growth factor (NGF) have proved as good therapeutic agents  Minocycline has shown as a neuro protective agent in Spinal cord injuries. Minocyline has exhibited good functional outcomes in paraplegic individuals Enzastaurin behaves by modulating cell survival pathways, potentially stopping cell death in the injured Spinal cord. Finally, it is concluded that the multi-dimensional nature of Paraplegia needs a comprehensive strategy and pharmacological interventions may play a critical role in enhancing the overall outcomes for individuals living with this challenging condition.


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References


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