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Understanding Nail Polish Removers: Chemical Principles, Performance, and Safety Assessment

jannat ul firdaus, Shahnawaz Ahmad, Anshika Yadav, Khushi Rastogi, Sarthak Tarar

Abstract


Nail polish removers serve as cosmetic products which remove nail polish while protecting the nails from damage. These products use organic solvents as their main ingredient with acetone being the most common choice because it dissolves substances quickly and customers can easily wash it off with water. The human body develops harmful effects from acetone when people use it too often because it causes their nails to lose moisture and become weak while their skin develops irritation and the area around their nails turns red. The cosmetic industry uses ethyl acetate and isopropyl alcohol as solvent alternatives which provide a less powerful but more expensive method for nail polish removal.

Nail polish removers operate by breaking down film-forming polymers which include nitrocellulose to enable nail lacquer dissolution and easy removal via wiping. Modern formulas reduce solvent damage by employing conditioning agents which contain glycerin and natural oils and vitamins to maintain moisture levels while they safeguard the nail surface. The advancements made in these products still face major challenges because people in work environments face dangers through toxic substances and inhalation exposure and long-term product usage.

Researchers now study methods to create safer and environmentally friendly products which include bio-based solvents and systems derived from plants and new product designs like gels and wipes. The environmental impact of VOC emissions and improper waste disposal practices demonstrates the necessity for biodegradable and environmentally sustainable solutions which should guide development of future product formulas.


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References


Abdullah, M. A., Hussein, H. A., & Alshajrawia, O. M. S. (2020a). Ethyl lactate as a green solvent in the pharmaceutical industry. In Green Sustainable Process for Chemical and Environmental Engineering and Science: Solvents for the Pharmaceutical Industry (pp. 185–194). Elsevier. https://doi.org/10.1016/B978-0-12-821885-3.00005-0

Akterian, S. (2020). Food Science and Applied Biotechnology Evaluating the vapour evaporation from the surface of liquid pure organic solvents and their mixtures. Food Science and Applied Biotechnology, 2020(1), 77–84. https://doi.org/10.30721/fsab2020.v3.i1

Alnuqaydan, A. M. (2024). The dark side of beauty: an in-depth analysis of the health hazards and toxicological impact of synthetic cosmetics and personal care products. In Frontiers in Public Health (Vol. 12). Frontiers Media SA. https://doi.org/10.3389/fpubh.2024.1439027

Arora, H., & Tosti, A. (2017). Safety and efficacy of nail products. In Cosmetics (Vol. 4, Number 3). MDPI AG. https://doi.org/10.3390/cosmetics4030024

Baswan, S., Kasting, G. B., Li, S. K., Wickett, R., Adams, B., Eurich, S., & Schamper, R. (2017). Understanding the formidable nail barrier: A review of the nail microstructure, composition and diseases. In Mycoses (Vol. 60, Number 5, pp. 284–295). Blackwell Publishing Ltd. https://doi.org/10.1111/myc.12592

Brown, J. J., & Nanayakkara, C. S. (2005). Acetone-free nail polish removers: Are they safe? Clinical Toxicology, 43(4), 297–299. https://doi.org/10.1081/CLT-200066081

Chemat, F., Vian, M. A., & Cravotto, G. (2012). Green extraction of natural products: Concept and principles. In International Journal of Molecular Sciences (Vol. 13, Number 7, pp. 8615–8627). MDPI AG. https://doi.org/10.3390/ijms13078615

Chen, H. J., Lee, P. Y., Chen, C. Y., Huang, S. L., Huang, B. W., Dai, F. J., Chau, C. F., Chen, C. S., & Lin, Y. S. (2022). Moisture retention of glycerin solutions with various concentrations: a comparative study. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-13452-2

de Paula, A. C., Uliana, F., da Silva Filho, E. A., & Luz, P. P. (2025). Nail Polishes: A Review on Composition, Presence of Toxic Components, and Inadequate Labeling. In Dermatology Research and Practice (Vol. 2025, Number 1). John Wiley and Sons Ltd. https://doi.org/10.1155/drp/6330337

Dilip, M., Andreatta, J. R., VanKirk, G., Aninakwa, A. D., & Parker, V. (2023). Teaching green chemistry, sustainability ethics, and toxicity using nail polish removers. Green Chemistry Letters and Reviews, 16(1). https://doi.org/10.1080/17518253.2023.2264322


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