Open Access Open Access  Restricted Access Subscription Access

Reporting and Observation of ADR by Nurses in Hospitalized Patients

Kumar Sanjay Hudda, Krishan Lal, Sachdeva Ajay, Himanshu ., Kaur Manjot, Deepika Nilesh Tank, D. Bhuvneshwari, A. Shoba Graciah, Pauline J. C., Baljeet Singh Khurana

Abstract


The important topics of adverse drug reactions (ADRs) are covered in this article, with an emphasis on managing, preventing, and identifying them. ADRs are described as adverse or unexpected drug reactions, and because of their variable severity, they require a sophisticated understanding. While not necessarily dangerous, side effects have the potential to develop into ADRs, which calls for action. The decision-making process entails evaluating the severity of the adverse reaction, the drug's possible advantages, and the patient's overall risk-benefit profile. When it comes to tracking and reporting adverse drug reactions (ADRs) to regulatory bodies for continuous medication safety evaluation, healthcare practitioners are essential. The classification of adverse drug reactions (ADRs) and identification techniques, such as clinical symptoms, patient reporting, and pharmacovigilance systems, are also covered in the article. Acute therapy, early detection, and drug cessation are critical components of management strategies, especially in the case of anaphylaxis. A comprehensive strategy that includes patient assessment, provider communication, education, and the use of electronic health information is required to prevent ADRs. Continuous improvement of drug safety is facilitated by active participation in pharmacovigilance programs and stakeholder collaboration. To improve overall medication safety and efficacy, the article's conclusion highlights the shared objective of reducing ADR occurrence and impact.


Full Text:

PDF

References


Aronson, J. K., & Ferner, R. E. (2003). Joining the DoTS: New approach to classifying adverse drug reactions. BMJ, 327, 1222–1225. https://doi.org/10.1136/bmj.327.7425.1222

Bouvy, J. C., De Bruin, M. L., & Koopmanschap, M. A. (2015). Epidemiology of adverse drug reactions in Europe: A review of recent observational studies. Drug Safety, 38(5), 437–453. https://doi.org/10.1007/s40264-015-0281-0

Cullen, D. J., Sweitzer, B. J., Bates, D. W., Burdick, E., Edmondson, A., & Leape, L. L. (1997). Preventable adverse drug events in hospitalized patients: A comparative study of intensive care and general care units. Critical Care Medicine, 25(8), 1289–1297. https://doi.org/10.1097/00003246-199708000-00014

Edwards, I. R., & Aronson, J. K. (2000). Adverse drug reactions: Definitions, diagnosis, and management. The Lancet, 356(9237), 1255–1259. https://doi.org/10.1016/S0140-6736(00)02799-9

Hakkarainen, K. M., Hedna, K., Petzold, M., & Hägg, S. (2012). Percentage of patients with preventable adverse drug reactions and preventability of adverse drug reactions: A meta-analysis. PLoS ONE, 7(3), e33236. https://doi.org/10.1371/journal.pone.0033236

Kees van Grootheest, K. V., Olsson, S., Couper, M., & de Jong-van den Berg, L. (Year unavailable). Pharmacists’ role in reporting adverse drug reactions in an international context.

Lazarou, J., Pomeranz, B. H., & Corey, P. N. (1998). Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies. JAMA, 279(15), 1200–1205. https://doi.org/10.1001/jama.279.15.1200

Multifaceted approach to reducing preventable adverse drug events. (2003). American Journal of Health-System Pharmacy, 60(6), 582–586.

Phillips, K. A., Veenstra, D. L., Oren, E., Lee, J. K., & Sadee, W. (2001). Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review. JAMA, 286(18), 2270–2279. https://doi.org/10.1001/jama.286.18.2270

Pirmohamed, M., James, S., Meakin, S., Green, C., Scott, A. K., Walley, T. J., ... & Breckenridge, A. M. (2004). Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18,820 patients. BMJ, 329(7456), 15–19. https://doi.org/10.1136/bmj.329.7456.15

Pir Mohamed, M., Breckenridge, A. M., & Ketteringham, N. R. (1998). Adverse drug reactions. BMJ, 316(7140), 1295–1298.

Rishi, R. K., Patel, R. K., & Bhandari, A. (2012). Under-reporting of ADRs by medical practitioners in India: Results of a pilot study. Advances in Pharmacoepidemiology & Drug Safety, 1(1), 1–3.

Rossi, A. C., Knapp, D. E., Anello, C., et al. (1983). Discovery of adverse drug reactions: A comparison of selected phase IV studies with spontaneous reporting methods. JAMA, 249(16), 2226–2228. https://doi.org/10.1001/jama.1983.03330400038025

Sharma, D., & Vervloet, D. (1998). Adverse reactions to drugs. BMJ, 316(7143), 1511–1514.

U.S. Food and Drug Administration (FDA). (2005). Guidance for industry: Good pharmacovigilance practices and pharmacoepidemiologic assessment. Center for Drug Evaluation and Research and Center for Biologics Evaluation and Research. https://www.fda.gov/media/71546/download

World Health Organization. (1972). International drug monitoring: The role of national centres. Report of a WHO Meeting. Geneva: World Health Organization.


Refbacks

  • There are currently no refbacks.