Exploring Drugs Targeting Neuroglial Disorders: A Comprehensive Overview
Abstract
Neurological disorders affect the intricate network of cells in the central nervous system (CNS) , along with neurons and glial cereals. Glial cells namely atrocities, oligodendro cytes and microbial play an important violence in controlling neural function, synaptic plasticity and overall CNS homeostasis. Anti_ inflammatory agents, namely NSAID and corticosteroids, have been explored for their potentiality in mitigating astrocyre _ mediated inflammation. Disease modifying drugs Including interferon and mono clonal antibodies, aim to modulate the immune response and decrease demyelination specifically in multiple sclerosis patients. Minocycline, an antibiotic with anti_ inflammatory properties, has proved beneficial effect in attenuating microbial activation and decreases neuro inflammation in many experimental models. Targeting glial fibrillary acidic protein ( GFAD ) , a marker for reactive atrocities has gained popularity. Small molecules and gene therapies aimed at modulating GFAP expression exhibit promise in regulating astrocyte reactivity and potentially decreasing the progression of neurological disorders. Finally it is concluded that the exploration of rugs targeting neurological disorders represents a promising avenue particularly in neuro science research.
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