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An Essential Parameters of Hereditary Fructose Intolerance Include Etiology, Epidemiology, Patho Physiology, Histo Pathology, Diagnosis, Differential Diagnosis, Treatment and Prognosis
Abstract
Patients with hereditary fructose intolerance, an autosomal recessive condition, do not have the enzyme necessary to break down fructose-1-phosphate. This illness typically manifests as nausea, vomiting, jaundice, and hypoglycemia during the weaning phase. Early detection is crucial, as is the quick implementation of dietary restrictions to reduce fructose.The evaluation and treatment of patients with genetic fructose intolerance are discussed in this activity, which also emphasizes the importance of an interdisciplinary team in the treatment of such patients.
References
Schrodi, S. J., DeBarber, A., He, M., Ye, Z., Peissig, P., Van Wormer, J. J., Haws, R., Brilliant, M. H., & Steiner, R. D. (2015). Prevalence estimation for monogenic autosomal recessive diseases using population-based genetic data. Human Genetics, 134(6), 659–669. https://doi.org/10.1007/s00439-015-1541-6
Seegmiller, J. E., Dixon, R. M., Kemp, G. J., Angus, P. W., McAlindon, T. E., Dieppe, P., Rajagopalan, B., & Radda, G. K. (1990). Fructose-induced aberration of metabolism in familial gout identified by 31P magnetic resonance spectroscopy. Proceedings of the National Academy of Sciences of the United States of America, 87(21), 8326–8330. https://doi.org/10.1073/pnas.87.21.8326
Quintana, E., Sturiale, L., Montero, R., Andrade, F., Fernandez, C., Couce, M. L., Barone, R., Aldamiz-Echevarria, L., Ribes, A., Artuch, R., & Briones, P. (2009). Secondary disorders of glycosylation in inborn errors of fructose metabolism. Journal of Inherited Metabolic Disease, 32(Suppl 1), S273–S278. https://doi.org/10.1007/s10545-009-1194-8
Aldámiz-Echevarría, L., de Las Heras, J., Couce, M. L., Alcalde, C., Vitoria, I., Bueno, M., Blasco-Alonso, J., García, M. C., Ruiz, M., Suárez, R., Andrade, F., & Villate, O. (2020). Non-alcoholic fatty liver in hereditary fructose intolerance. Clinical Nutrition, 39(2), 455–459. https://doi.org/10.1016/j.clnu.2019.02.030
Ali, M., Rellos, P., & Cox, T. M. (1998). Hereditary fructose intolerance. Journal of Medical Genetics, 35(5), 353–365. https://doi.org/10.1136/jmg.35.5.353
Bouteldja, N., & Timson, D. J. (2010). The biochemical basis of hereditary fructose intolerance. Journal of Inherited Metabolic Disease, 33(2), 105–112. https://doi.org/10.1007/s10545-010-9054-5
Newbrun, E., Hoover, C., Mettraux, G., & Graf, H. (1980). Comparison of dietary habits and dental health of subjects with hereditary fructose intolerance and control subjects. Journal of the American Dental Association, 101(4), 619–626. https://doi.org/10.14219/jada.archive.1980.0354
Mettraux, G., Graf, H., Newbrun, E., & Hoover, C. (1980). Dental plaque composition, caries occurrence and nutritional habits of patients with hereditary fructose intolerance (HFI). Schweizerische Monatsschrift für Zahnheilkunde, 90(9), 881–896.
Maggiore, G., & Borgna-Pignatti, C. (1982). Disseminated intravascular coagulation associated with hereditary fructose intolerance. American Journal of Diseases of Children, 136(2), 169–170. https://doi.org/10.1001/archpedi.1982.03970380039017
Mock, D. M., Perman, J. A., Thaler, M., & Morris, R. C. (1983). Chronic fructose intoxication after infancy in children with hereditary fructose intolerance: A cause of growth retardation. New England Journal of Medicine, 309(13), 764–770. https://doi.org/10.1056/NEJM198309293091302
Hosková, A., & Mrskos, A. (1977). Fructose intolerance—A severe disease of young nursing infants. Československá Pediatrie, 32(8), 495–496.
Marks, F., Ordorica, S., Hoskins, I., & Young, B. K. (1989). Congenital hereditary fructose intolerance and pregnancy. American Journal of Obstetrics and Gynecology, 160(2), 362–363. https://doi.org/10.1016/0002-9378(89)90403-0
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