Pattern of Self-Reported Allergies and Medication-Related Reactions Among Second-Year Diploma in Pharmacy Students: A Cross-Sectional Survey
Abstract
Background: Allergic conditions and medication-related reactions are crucial in medication safety, as inaccurate classification of allergies can impact medication use and clinical decisions. It is essential for pharmacy practice to differentiate true allergic reactions from other medication-related symptoms.
Objective: To evaluate self-reported allergies, environmental and familial influences, and reactions to medications, particularly antibiotics, in second-year Diploma in Pharmacy students..
Method: A cross-sectional survey was conducted with 35 second-year Diploma in Pharmacy students to assess various factors related to allergies. Data were collected over two days via a structured questionnaire administered through Google Forms, covering demographic characteristics, types of allergies, confirmation of allergies, environmental influences, medication-related symptoms, and reactions to antibiotics, including skin manifestations and severity. Data analysis was performed using frequencies and percentages after exporting to Google Sheets/Microsoft Excel.
Result: Of the 35 respondents, 77.1% were aged 20-29 years. The most common allergy was food allergy (40.0%), followed by drug allergy (22.9%). 57.1% reported their allergies were confirmed by self-report, without independent verification. Hand eczema was noted by 45.7% of participants. 82.9% had never been prescribed adrenaline/epinephrine, and 65.7% reported no medication-related symptoms. Among 34 responses to severity, 50.0% chose “other,” 20.6% reported moderate reactions, and 17.6% reported mild-to-moderate reactions.
Conclusion: The survey revealed self-reported food and drug allergies, skin manifestations, and medication-related symptoms in second-year D.Pharm students, trigger identification, and patient education. Due to the small sample size of 35 students and reliance on self-reported data, findings should not be seen as representative of the broader population. Recommendations include larger studies with standardized definitions and clinical assessments.
References
Albin, S., & Agarwal, S. (2014). Prevalence and characteristics of reported penicillin allergy in an urban outpatient adult population. Allergy and asthma proceedings, 35(6), 489–494. https://doi.org/10.2500/aap.2014.35.3791.
Macy, E., & Contreras, R. (2014). Health care use and serious infection prevalence associated with penicillin “allergy” in the United States. Journal of Allergy and Clinical Immunology, 133(3), 790–796. https://doi.org/10.1016/j.jaci.2013.09.021.
Blumenthal, K. G., Lu, N., Zhang, Y., Li, Y., Walensky, R. P., & Choi, H. K. (2018). Risk of meticillin resistant Staphylococcus aureus and Clostridium difficile in patients with a documented penicillin allergy: Population based matched cohort study. BMJ, 361, k2400. https://doi.org/10.1136/bmj.k2400 .
Trubiano, J. A., Cairns, K. A., Evans, J. A., & others. (2017). The prevalence and clinical impact of antibiotic allergy labels in hospitalized patients. Journal of Antimicrobial Chemotherapy, 72(8), 2466–2473.
Blumenthal, K. G., Peter, J. G., Trubiano, J. A., & Phillips, E. J. (2019). Antibiotic allergy. The Lancet, 393(10167), 183–198. https://doi.org/10.1016/S0140-6736(18)32218-9
Trubiano, J. A., Vogrin, S., Chua, K. Y. L., Bourke, J., Yun, J., Douglas, A. P., Stone, C. A., Phillips, E. J., & others. (2020). Development and validation of a penicillin allergy clinical decision rule. JAMA Internal Medicine, 180(5), 745–752. https://doi.org/10.1001/jamainternmed.2020.0403
Wang, L., et al. (2020). A dynamic reaction picklist for improving allergy reaction documentation in the electronic health record. Journal of the American Medical Informatics Association, 27(6), 917–923. https://doi.org/10.1093/jamia/ocaa042
Shenoy, E. S., Macy, E., Rowe, T., & Blumenthal, K. G. (2019). Evaluation and management of penicillin allergy: A review. JAMA, 321(2), 188–199. https://doi.org/10.1001/jama.2018.19283
Sacco, K. A., Bates, A., Brigham, T. J., Imam, J. S., & Burton, M. C. (2017). Clinical outcomes following inpatient penicillin allergy testing: A systematic review and meta-analysis. Allergy, 72(9), 1288–1296. https://doi.org/10.1111/all.13168
Zhou, L., Dhopeshwarkar, N., Blumenthal, K. G., Goss, F., Qu, Y., & others. (2016). Drug allergies documented in electronic health records of hospitalized patients. Journal of Allergy and Clinical Immunology: In Practice, 4(5), 962–968.
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