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Understanding the Impact of Drugs on Thalamic pain syndrome in Humans
Abstract
Stimulants enhance neurotransmitter activity in the brain including dopamine and nor epinephrine which can alter Thalamic function. Deoressants such as alcohol and benzo diazepines decrease neural activity along with thalamus, leading to the sedation as well as impaired sensory processing. Opioid bind to opioid receptors in various brain regions including the thalamus, modulating pain perception and mood. Cannabinoids interact with the endo cannabinoid system, which modulate neuro transmitter release throughout the brain, including the thalamus. Finally it is concluded that the thalamus serves as a critical relay station for sensory and motor signals in the brain, making it susceptible to modulation by various drugs.
References
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