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A review of analytical methods for Vinpocetine, its impurities, and pharmaceutical formulations.

Chetan Chandrakant Bhadane, S. P. Pawar, Amitkumar R. Dhankani, Mansi A Dhankani

Abstract


Vinpocetine (ethyl-apovincamine-22-oate, VP), a derivative of the alkaloid vincamine (commercial name Cavinton), has emerged as a captivating neuroprotective agent with promising applications in cognitive enhancement and vascular health. This review aims to provide a comprehensive overview of the diverse array of analytical methods employed for the analysis of Vinpocetine and ionic impurities in pharmaceutical compounds. The review will explore the challenges faced by researchers and analysts in this specialized field, as well as the innovative solutions and advancements that have been made to address these challenges. Moreover, this review will highlight the importance of method validation, calibration strategies, and quality control measures, as these aspects play a crucial role in ensuring the accuracy, precision, and reproducibility of analytical results. In addition, the review will discuss the development of novel analytical methodologies for the characterization of pharmacokinetics, including mass spectrometry and chromatographic techniques.


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References


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